Brain changes, weight loss, and even infection history could help pinpoint who might be at risk

A senior black man is sitting in his doctor's office and listening as the doctor shows him something on a digital tablet.

Alzheimer’s disease and other related dementias are characterized by progressive cognitive decline, and with an aging population, the number of older Americans with dementia is expected to rise dramatically in coming years. But dementia is not an inevitable part of aging.

New studies funded by the National Institute on Aging (NIA) identify early warning signs of cognitive decline and key factors that contribute to dementia risk. Early diagnosis allows access to treatments that can delay the onset or slow the development of dementia, improving the health and well-being of dementia patients and their caregivers and reducing health care costs.


Paola Scommegna, Mark Mather, Dan Vahaba (January 2025). New Studies Identify Early Warning Signs of Dementia. Population Reference Bureau.

Yuan S. Zhang and Virginia W. Chang, “Time Path of Weight Status Before and After Incident Dementia,” Journal of Aging and Health 36, no. 1–2 (2024): 98–109.

Leah S. Richmond-Rakerd et al., “Associations of Hospital-Treated Infections With Subsequent Dementia: Nationwide 30-Year Analysis,” Nature Aging 4, no. 6 (2024): 783–90.

Brian Downer et al., “Dual-Language Use and Cognitive Function Among Mexican Americans Aged 65 and Older,” Journal of Alzheimer’s Disease 99, no. 3 (2024): 1105–15.